In vitro and in vivo potentialities for cartilage repair from human advanced knee osteoarthritis synovial fluid-derived mesenchymal stem cells.

Fiche publication

Date publication

novembre 2018

Journal

Stem cell research & therapy

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GILLET Pierre , Pr MAINARD Didier

Tous les auteurs :
Neybecker P, Henrionnet C, Pape E, Mainard D, Galois L, Loeuille D, Gillet P, Pinzano A

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/30486903

Résumé

Mesenchymal stem cells (MSCs) are found in synovial fluid (SF) and can easily be harvested during arthrocentesis or arthroscopy. However, SF-MSC characterization and chondrogenicity in collagen sponges have been poorly documented as well as their hypothetical in vivo chondroprotective properties with intra-articular injections during experimental osteoarthritis (OA).