Hepatitis E Virus-Induced Primary Cutaneous CD30(+) T cell Lymphoproliferative Disorder.

Date publication

août 2017

Journal

Journal of hepatology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HILLON Patrick

Tous les auteurs :
Mallet V, Bruneau J, Zuber J, Alanio C, Leclerc-Mercier S, Roque-Afonso AM, Kraft ARM, Couronné L, Roulot D, Wedemeyer H, Albert ML, Hillon P, Laroche L, Pol S, Hermine O

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/28860025

Résumé

Several types of unexplained extra-hepatic manifestations, including haematological disorders, have been reported in the context of hepatitis E virus (HEV) infection. However, the underlying mechanism(s) of these manifestations are unknown. We provide evidence that HEV has an extra-hepatic endothelial tropism that can engage cutaneous T cells towards clonality.

Mots clés

CD30-positive cutaneous T cell lymphoproliferative disorder, Endothelial cell, Extra-hepatic manifestation, HEV, Hepatitis E, Lymphoma, Lymphomatoid papulosis, Non-Hodgkin lymphoma

Référence

J. Hepatol.. 2017 Aug;: