Down-regulation of A-FABP predicts non-muscle invasive bladder cancer progression: investigation with a long term clinical follow-up.

Fiche publication

Date publication

décembre 2018

Journal

BMC cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BITTARD Hugues , Dr LASCOMBE Isabelle , Mr MONNIEN Franck , Dr FAUCONNET Sylvie , Pr KLEINCLAUSS François

Tous les auteurs :
Mathis C, Lascombe I, Monnien F, Bittard H, Kleinclauss F, Bedgedjian I, Fauconnet S, Valmary-Degano S

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/30526555

Résumé

Non-muscle invasive bladder cancers (NMIBC: pTa, pT1) are characterised by a high risk of recurrence and/or progression. Identification of prognostic markers is needed to improve both diagnosis and management of the disease. The aim of this study was to analyse the expression of A-FABP (adipocyte-fatty acid binding protein) and to evaluate its prognostic value in bladder cancer with a long term clinical follow-up.