Fiche publication
Date publication
juin 2017
Journal
Dalton transactions (Cambridge, England : 2003)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BETTAIEB Ali
,
Pr PAUL Catherine
Tous les auteurs :
Trommenschlager A, Chotard F, Bertrand B, Amor S, Dondaine L, Picquet M, Richard P, Bettaïeb A, Le Gendre P, Paul C, Goze C, Bodio E
Lien Pubmed
Résumé
Two new gold(i)-BODIPY-imidazole based trackable therapeutic bimetallic complexes have been synthesized and fully characterized. They display strong antiproliferative properties on several types of cancers including colon, breast, and prostate and one of them presents a significant anti-inflammatory effect. Additionally, the two compounds could be visualised in vitro by confocal microscopy in the submicromolar range.
Mots clés
Anti-Inflammatory Agents, chemical synthesis, Antineoplastic Agents, chemical synthesis, Boron Compounds, chemistry, Cell Line, Tumor, Cell Proliferation, drug effects, Coordination Complexes, chemical synthesis, Drug Discovery, Fluorescent Dyes, chemistry, Gold, chemistry, Humans, Imidazoles, chemistry
Référence
Dalton Trans. 2017 Jun;:
