Fiche publication


Date publication

juin 2017

Journal

Pediatric blood & cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Pr CHASTAGNER Pascal


Tous les auteurs :
Lemelle L, Pierron G, Fréneaux P, Huybrechts S, Spiegel A, Plantaz D, Julieron M, Dumoucel S, Italiano A, Millot F, Le Tourneau C, Leverger G, Chastagner P, Carton M, Orbach D

Résumé

Nuclear protein of the testis (NUT) carcinoma (formerly NUT midline carcinoma) is an aggressive tumor defined by the presence of NUT rearrangement with a poor prognosis. This rare cancer is underdiagnosed and poorly treated.

Mots clés

NUT carcinoma, NUT gene, NUT midline carcinoma, bromodomain and extraterminal (BET) protein, chemotherapy, histone deacetylase

Référence

Pediatr Blood Cancer. 2017 Jun;: