FDG Brain PET/CT Revealing Bilateral Thalamostriatal Activation During a Symptomatic Episode in a Patient With Kleine-Levin Syndrome.

Date publication

mai 2017

Journal

Clinical nuclear medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr VERGER Antoine , Pr BOULAHDOUR Hatem

Tous les auteurs :
Drouet C, Morel O, Verger A, Guedj E, Boulahdour H

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/28221196

Résumé

We report the case of a 14-year-old girl with clinically diagnosed Kleine-Levin syndrome. Electroencephalogram and brain MRI were unremarkable. An FDG PET/CT scan was acquired during a symptomatic episode, while she was asleep, and another PET scan was obtained when she was asymptomatic, awake, and quiet. Comparison of both examinations demonstrated a bilateral activation of thalami, caudate nuclei, and lenticular nuclei. These findings may be linked to the implication of thalamostriatal structures in the regulation of sleep and wakefulness.

Mots clés

Adolescent, Brain, diagnostic imaging, Female, Fluorodeoxyglucose F18, Humans, Kleine-Levin Syndrome, diagnostic imaging, Positron Emission Tomography Computed Tomography, Radiopharmaceuticals

Référence

Clin Nucl Med. 2017 May;42(5):e261-e262