High-Frequency Neuronavigated rTMS in Auditory Verbal Hallucinations: A Pilot Double-Blind Controlled Study in Patients With Schizophrenia.

Date publication

avril 2018

Journal

Schizophrenia bulletin

Auteurs

Membres identifiés du Cancéropôle Est :
Pr TROJAK Benoît

Tous les auteurs :
Dollfus S, Jaafari N, Guillin O, Trojak B, Plaze M, Saba G, Nauczyciel C, Montagne Larmurier A, Chastan N, Meille V, Krebs MO, Ayache SS, Lefaucheur JP, Razafimandimby A, Leroux E, Morello R, Marie Batail J, Brazo P, Lafay N, Wassouf I, Harika-Germaneau G, Guillevin R, Guillevin C, Gerardin E, Rotharmel M, Crépon B, Gaillard R, Delmas C, Fouldrin G, Laurent G, Nathou C, Etard O

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29897597

Résumé

Despite extensive testing, the efficacy of low-frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS) of temporo-parietal targets for the treatment of auditory verbal hallucinations (AVH) in patients with schizophrenia is still controversial, but promising results have been reported with both high-frequency and neuronavigated rTMS. Here, we report a double-blind sham-controlled study to assess the efficacy of high-frequency (20 Hz) rTMS applied over a precise anatomical site in the left temporal region using neuronavigation.

Mots clés

Adult, Double-Blind Method, Female, Hallucinations, etiology, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neuronavigation, methods, Outcome Assessment (Health Care), Psychotic Disorders, complications, Schizophrenia, complications, Temporal Lobe, physiopathology, Transcranial Magnetic Stimulation, methods

Référence

Schizophr Bull. 2018 04 6;44(3):505-514