Highly sensitive assessment of neuroblastoma minimal residual disease in ovarian tissue using RT-qPCR-A strategy for improving the safety of fertility restoration.

Date publication

mai 2017

Journal

Pediatric blood & cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Dr AMIOT Clotilde

Tous les auteurs :
Grèze V, Brugnon F, Chambon F, Halle P, Canis M, Amiot C, Grémeau AS, Pereira B, Yáñez Peralta Y, Tchirkov A, Kanold J

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/27734578

Résumé

Ovarian tissue cryopreservation (OTC) is the only option available to preserve fertility in prepubertal females with neuroblastoma (NB), a childhood solid tumor that can spread to the ovaries, with a risk of reintroducing malignant cells after an ovarian graft.

Mots clés

RT-qPCR, fertility preservation, minimal residual disease, neuroblastoma, ovarian tissue

Référence

Pediatr Blood Cancer. 2017 May;64(5):