Systematic review of the influence of chemotherapy-associated liver injury on outcome after partial hepatectomy for colorectal liver metastases.

Date publication

mai 2017

Journal

The British journal of surgery

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PESSAUX Patrick

Tous les auteurs :
Zhao J, van Mierlo KMC, Gómez-Ramírez J, Kim H, Pilgrim CHC, Pessaux P, Rensen SS, van der Stok EP, Schaap FG, Soubrane O, Takamoto T, Viganò L, Winkens B, Dejong CHC, Olde Damink SWM,

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/28542731

Résumé

The impact of chemotherapy-associated liver injury (CALI) on postoperative outcome in patients undergoing partial hepatectomy for colorectal liver metastases (CRLM) remains controversial. The objective of this study was to clarify the effect of CALI (sinusoidal dilatation (SD), steatosis and steatohepatitis) on postoperative morbidity and mortality by investigating a large data set from multiple international centres.

Mots clés

Antineoplastic Combined Chemotherapy Protocols, adverse effects, Chemical and Drug Induced Liver Injury, complications, Colorectal Neoplasms, Fatty Liver, chemically induced, Female, Hepatectomy, methods, Humans, Length of Stay, Liver Failure, Acute, etiology, Liver Neoplasms, mortality, Male, Middle Aged, Postoperative Complications, etiology

Référence

Br J Surg. 2017 May;: