Fiche publication
Date publication
juillet 2014
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ANSELME Karine
Tous les auteurs :
Sima F, Axente E, Iordache I, Luculescu C, Gallet O, Anselme K, Mihailescu N
Résumé
Defined protein quantities were embedded in situ in a biodegradable polymer coating during simultaneous laser vaporization of two targets. Fibronectin (FN) and poly-DL-lactide (PDLLA) were transferred and immobilized concomitantly by Combinatorial Matrix Assisted Pulsed Laser Evaporation onto solid substrates. The film surface with gradient of composition was characterized by optical, scanning electron microscopy and profilometry. Micrometric FN packages were visualized in the polymeric matrix by confocal microscopy. The composition of FN was investigated by FUR and tiFTIR analyses in a polymeric matrix with different thickness. (C) 2014 Elsevier B.V. All rights reserved.
Référence
Appl Surf Sci. 2014 Jul 1;306:75-9.
