Gain in the short arm of chromosome 2 (2p+) induces gene overexpression and drug resistance in chronic lymphocytic leukemia: Analysis of the central role of XPO1.

Date publication

mars 2017

Journal

Leukemia

Auteurs

Membres identifiés du Cancéropôle Est :
Pr FEUGIER Pierre

Tous les auteurs :
Cosson A, Chapiro E, Bougacha N, Lambert J, Herbi L, Cung HA, Algrin C, Keren B, Damm F, Gabillaud C, Brunelle-Navas MN, Davi F, Merle-Béral H, Le Garff-Tavernier M, Roos-Weil D, Choquet S, Uzunov M, Morel V, Leblond V, Maloum K, Leprêtre S, Feugier P, Lesty C, Lejeune J, Sutton L, Landesman Y, Susin SA, Nguyen-Khac F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/28344316

Résumé

Leukemia accepted article preview online, 27 March 2017. doi:10.1038/leu.2017.100.

Mots clés

Apoptosis, Chromosomes, Human, Pair 2, Drug Resistance, Neoplasm, drug effects, Gene Expression Regulation, Leukemic, Humans, Hydrazines, pharmacology, Karyopherins, genetics, Leukemia, Lymphocytic, Chronic, B-Cell, drug therapy, Receptors, Cytoplasmic and Nuclear, genetics, Triazoles, pharmacology

Référence

Leukemia. 2017 Mar;: