Fiche publication
Date publication
décembre 2017
Journal
International journal of medical microbiology : IJMM
Auteurs
Membres identifiés du Cancéropôle Est :
Dr D'AVENI-PINEY Maud
,
Pr GALLET Patrice
Tous les auteurs :
Dorin J, D'Aveni M, Debourgogne A, Cuenin M, Guillaso M, Rivier A, Gallet P, Lecoanet G, Machouart M
Lien Pubmed
Résumé
Actinomucor elegans is a fungus belonging to mucormycetes and is still probably underdiagnosed due to misidentification. Based on a recent first case of Actinomucor elegans sinusitis in Europe, in an immunocompromised patient under voriconazole treatment, this paper aims to summarize knowledge about A. elegans mucormycoses. Even if the diagnosis of mucormycosis was made using traditional mycology techniques, precise identification of the fungus could only be achieved using molecular tools. In this observation, the galactomannan dosage was positive until the introduction of treatment and surgical debridement. The patient experienced no relapse after one year. By reviewing the four previous A. elegans reported cases and describing the mycological characteristics of this species, we highlight the need to use a combination of tools to improve the diagnostic strategy in such rare and life-threatening clinical situations.
Mots clés
Adult, Antifungal Agents, administration & dosage, Debridement, Europe, Humans, Immunocompromised Host, Male, Mannans, blood, Mucorales, classification, Mucormycosis, diagnosis
Référence
Int. J. Med. Microbiol.. 2017 Dec;307(8):435-442
