Fiche publication
Date publication
février 2019
Journal
World neurosurgery
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NOEL Georges
,
Dr LHERMITTE Benoît
,
Dr CEBULA Hélène
,
Pr PROUST François
Tous les auteurs :
Gubian A, Ganau M, Cebula H, Todeschi J, Scibilia N, Noel G, Spatola G, Chaussemy D, Nannavecchia B, P G, Coca A, Pop R, Signorelli F, Proust F, Lhermitte B, Chibbaro S
Lien Pubmed
Résumé
Intracranial solitary fibrous tumors (ISFT) are rare mesenchymal neoplasms, originating in the meninges, characterized by very different biological and clinical behaviors. Benign histotypes such as hemangiopericytomas are now considered a cellular phenotypic variant of this heterogeneous group of rare spindle-cell tumors. Due to their rarity and resemblance to other more common brain tumors, ISFTs are often poorly recognized and remain a diagnostic challenge: in fact, ISFT might either have a benign/indolent clinical behavior or show biological aggressivity with local and distant recurrences after surgery. We describe herein a surgical series of 29 patients treated for ISFTs confirmed histologically and through immunohistochemistry. We attempt to provide a focus on the natural history of these pathologies and the need for a tailored management.
Mots clés
Anaplasia, Hemangiopericytoma, Intracranial Solitary Fibrous Tumours, Radiotherapy, Recurrence
Référence
World Neurosurg. 2019 Feb 1;:
