ARLTS1, potential candidate gene in familial aggregation of hematological malignancies.

Date publication

février 2017

Journal

Bulletin du cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Pr FAIVRE Laurence

Tous les auteurs :
Hamadou WS, Besbes S, Mani R, Bourdon V, Ben Youssef Y, Achour B, Regaieg H, Eisinger F, Mari V, Gesta P, Dreyfus H, Bonadona V, Dugast C, Zattara H, Faivre L, Noguchi T, Khélif A, Sobol H, Soua Z

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/27866680

Résumé

Genetic predisposition to familial hematological malignancies was previously described through several epidemiological analyses, but the genetic basis remains unclear. The tumor-suppressor ARLTS1 gene was previously described in sporadic hematological malignancies and familial cancer context.

Mots clés

ADP-Ribosylation Factors, genetics, Breast Neoplasms, genetics, Cohort Studies, Female, France, Genes, Tumor Suppressor, Genetic Predisposition to Disease, Genetic Variation, Hematologic Neoplasms, genetics, Humans, Leukemia, Lymphocytic, Chronic, B-Cell, genetics, Male, Tunisia

Référence

Bull Cancer. 2017 Feb;104(2):123-127