Fiche publication
Date publication
mars 2019
Journal
The journal of obstetrics and gynaecology research
Auteurs
Membres identifiés du Cancéropôle Est :
Dr CHAUSSY Yann
Tous les auteurs :
Mottet N, Metz JP, Chaussy Y
Lien Pubmed
Résumé
This report is aimed at opening a new reflexion about exploration of fetal lungs malformations with 2-D ultrasound shear wave elastography (2D-SWE) in two fetuses. These preliminary results are drawn from the ELASTOMAP study, which was designed to explore feasibility of 2D-SWE on fetal lungs. Fetus A presented Congenital Pulmonary Airway Malformation and fetus B congenital obstructive emphysema. We estimated every 3 weeks the Congenital Pulmonary Airway Malformation Volume Ratio (CVR) of the malformation and we evaluated stiffness by 2D-SWE. Stiffness of the lesion and the normal lung were compared to liver stiffness using Lung to Liver Elastography (LLE) ratio. Interestingly, CVR and LLE ratios evolved differently in these two lesions caused by distinct physiopathological processes. In both cases, LLE ratio' variations preceded that of CVR. LLE ratio of the normal lung was constant through gestation. 2D-SWE could be a promising tool to describe stiffness evolution in fetal lungs malformations.
Mots clés
congenital malformation, lung pathology, prenatal imaging, stiffness
Référence
J. Obstet. Gynaecol. Res.. 2019 Mar 10;:
