Fiche publication
Date publication
mai 2019
Journal
Nanotechnology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr WEISS Etienne
,
Dr ZUBER Guy
Tous les auteurs :
Zuber G, Weiss E, Chiper M
Lien Pubmed
Résumé
The latest advances concerning ultra-small gold nanoparticles (≤ 2 nm) commonly known as gold nanoclusters (AuNCs) are reviewed and discussed in the context of biological and biomedical applications (labeling, delivery, imaging and therapy). A great diversity of synthetic methods has been developed and optimized aiming to improve the chemical structures and physico-chemical properties of the resulting AuNCs. The main synthetic approaches were surveyed with emphasis on methods leading to water-soluble AuNCs since aqueous solutions are the preferred media for biological applications. The most representative and recent experimental results are discussed in relationship to their potential for biomedical applications.
Mots clés
bioimaging, cancer imaging, cancer therapy, drug delivery, gold nanoclusters, molecular nanoprobes
Référence
Nanotechnology. 2019 May 9;:
