Fiche publication
Date publication
février 2019
Journal
EBioMedicine
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BERTAUT Aurélie
,
Dr COLLIN Françoise
,
Pr MERLIN Jean-Louis
,
Dr MIRJOLET Céline
,
Pr NOEL Georges
,
Pr TRUC Gilles
Tous les auteurs :
Mirjolet C, Merlin JL, Truc G, Noël G, Thariat J, Domont J, Sargos P, Renard-Oldrini S, Ray-Coquard I, Liem X, Chevreau C, Lagrange JL, Mahé MA, Collin F, Bonnetain F, Bertaut A, Maingon P
Lien Pubmed
Résumé
Radiation-induced sarcoma (RIS) is a rare but serious event. Its occurrence has been discussed during the implementation of new radiation techniques and justified appropriate radioprotection requirements. New approaches targeting intrinsic radio-sensitivity have been described, such as radiation-induced CD8 T-lymphocyte apoptosis (RILA) able to predict late radio-induced toxicities. We studied the role of RILA as a predisposing factor for RIS as a late adverse event following radiation therapy (RT).
Référence
EBioMedicine. 2019 Feb 28;:
