Receptor for advanced glycation end products: a key molecule in the genesis of chronic kidney disease vascular calcification and a potential modulator of sodium phosphate co-transporter PIT-1 expression.

Date publication

février 2019

Journal

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GILLERY Philippe , Dr BOULAGNON-ROMBI Camille

Tous les auteurs :
Belmokhtar K, Ortillon J, Jaisson S, Massy ZA, Boulagnon Rombi C, Doué M, Maurice P, Fritz G, Gillery P, Schmidt AM, Rieu P, Touré F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/30778553

Résumé

Chronic kidney disease (CKD) is associated with increased cardiovascular mortality, frequent vascular calcification (VC) and accumulation of uraemic toxins. Advanced glycation end products and S100 proteins interact with the receptor for advanced glycation end products (RAGE). In the present work, we aimed to investigate the role(s) of RAGE in the CKD-VC process.

Référence

Nephrol. Dial. Transplant.. 2019 Feb 18;: