Gastrointestinal Disorder Associated with Olmesartan Mimics Autoimmune Enteropathy.

Date publication

janvier 2015

Journal

PloS one

Auteurs

Membres identifiés du Cancéropôle Est :
Pr CADIOT Guillaume , Dr VUITTON Lucine

Tous les auteurs :
Scialom S, Malamut G, Meresse B, Guegan N, Brousse N, Verkarre V, Derrieux C, Macintyre E, Seksik P, Savoye G, Cadiot G, Vuitton L, Marthey L, Carbonnel F, Cerf-Bensussan N, Cellier C

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/26101883

Résumé

Anti-hypertensive treatment with the angiotensin II receptor antagonist olmesartan is a rare cause of severe Sprue-like enteropathy. To substantiate the hypothesis that olmesartan interferes with gut immune homeostasis, clinical, histopathological and immune features were compared in olmesartan-induced-enteropathy (OIE) and in autoimmune enteropathy (AIE).

Mots clés

Adolescent, Adult, Aged, Angiotensin II Type 1 Receptor Blockers, adverse effects, Diagnosis, Differential, Female, Gastrointestinal Diseases, chemically induced, Humans, Imidazoles, adverse effects, Male, Middle Aged, Polyendocrinopathies, Autoimmune, diagnosis, Tetrazoles, adverse effects, Young Adult

Référence

PLoS ONE. 2015 ;10(6):e0125024