Fiche publication


Date publication

novembre 2011

Journal

The American journal of gastroenterology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr OUSSALAH Abderrahim , Pr PEYRIN-BIROULET Laurent


Tous les auteurs :
Roblin X, Pillet S, Oussalah A, Berthelot P, Del Tedesco E, Phelip JM, Chambonnière ML, Garraud O, Peyrin-Biroulet L, Pozzetto B

Résumé

Previous studies have suggested an association between cytomegalovirus (CMV) infection and steroid-refractory inflammatory bowel disease. In this study, the use of CMV DNA load during acute flare-ups of ulcerative colitis (UC) to predict resistance to immunosuppressive therapy was evaluated in intestinal tissue.

Mots clés

Adrenal Cortex Hormones, therapeutic use, Adult, Antibodies, Viral, blood, Antiviral Agents, therapeutic use, Colitis, Ulcerative, drug therapy, Cytomegalovirus, immunology, Cytomegalovirus Infections, complications, DNA, Viral, analysis, Drug Resistance, Female, Ganciclovir, therapeutic use, Humans, Immunosuppressive Agents, therapeutic use, Intestinal Mucosa, virology, Male, Middle Aged, Prospective Studies, ROC Curve, Real-Time Polymerase Chain Reaction, Viral Load

Référence

Am. J. Gastroenterol.. 2011 Nov;106(11):2001-8