Systematic review with meta-analysis: comparative efficacy of biologics for induction and maintenance of mucosal healing in Crohn's disease and ulcerative colitis controlled trials.

Date publication

mai 2017

Journal

Alimentary pharmacology & therapeutics

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent

Tous les auteurs :
Cholapranee A, Hazlewood GS, Kaplan GG, Peyrin-Biroulet L, Ananthakrishnan AN

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/28326566

Résumé

Mucosal healing is an important therapeutic endpoint in the management of Crohn's disease (CD) and ulcerative colitis (UC). Limited data exist regarding the comparative efficacy of various therapies in achieving this outcome.

Mots clés

Antibodies, Monoclonal, therapeutic use, Biological Factors, therapeutic use, Biological Products, therapeutic use, Colitis, Ulcerative, drug therapy, Crohn Disease, drug therapy, Humans, Immunosuppressive Agents, therapeutic use, Induction Chemotherapy, Maintenance Chemotherapy, Mucous Membrane, drug effects, Randomized Controlled Trials as Topic, Treatment Outcome, Wound Healing, drug effects

Référence

Aliment. Pharmacol. Ther.. 2017 May;45(10):1291-1302