Fiche publication
Date publication
août 2014
Journal
Annals of surgical oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BEDENNE Laurent
,
Dr BOUVIER Anne-Marie
,
Pr LEPAGE Côme
Tous les auteurs :
Hamza S, Bouvier AM, Rollot F, Lepage C, Faivre J, Bedenne L
Lien Pubmed
Résumé
Results concerning the side effects of oxaliplatin associated with fluorouracil and leucovorin (FOLFOX) in older patients are controversial. The objective of this study was to assess the use and the toxicity of FOLFOX in patients aged 70 years and older as administered in current practice.
Mots clés
Adenocarcinoma, drug therapy, Aged, Antineoplastic Combined Chemotherapy Protocols, adverse effects, Cohort Studies, Colonic Neoplasms, drug therapy, Digestive System Diseases, chemically induced, Female, Fluorouracil, administration & dosage, Follow-Up Studies, France, epidemiology, Hematologic Diseases, chemically induced, Humans, Incidence, Leucovorin, administration & dosage, Male, Neoplasm Staging, Nervous System Diseases, chemically induced, Organoplatinum Compounds, administration & dosage, Prognosis, Survival Rate
Référence
Ann. Surg. Oncol.. 2014 Aug;21(8):2636-41