An aqueous extract of the Anogeissus leiocarpus bark (AEAL) induces the endothelium-dependent relaxation of porcine coronary artery rings involving predominantly nitric oxide.

Fiche publication

Date publication

novembre 2018

Journal

Journal of basic and clinical physiology and pharmacology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr SCHINI-KERTH Valérie , Dr AUGER Cyril

Tous les auteurs :
Belemnaba L, Ouédraogo S, Nitiéma M, Chataigneau T, Guissou IP, Schini-Kerth VB, Bucher B, Auger C

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29723154

Résumé

Anogeissus leiocarpus is a Sahel tree traditionally used by the residents of Burkina Faso for its antihypertensive properties. In this study, experiments were conducted to evaluate whether an aqueous extract of the Anogeissus leiocarpus (AEAL) trunk bark induces a vasorelaxant effect on porcine coronary artery rings and to investigate the underlying mechanism.