Fiche publication
Journal
The journal of gene medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DE CARVALHO BITTENCOURT Marcelo
,
Dr FERRAND Christophe
,
Dr PERRUCHE Sylvain
Tous les auteurs :
de Carvalho Bittencourt M, Saas P, Fresnay S, Yerly-Motta V, Ferrand C, Perruche S, Duperrier A, Hervé P, Tiberghien P, Chalmers DE
Lien Pubmed
Résumé
Gene-transfer techniques are commonly employed for both in vitro and in vivo studies. However, modifications of the target cell following the introduction of the gene of interest are not often examined. These modifications can alter the immunogenicity and/or the susceptibility of the target cell to apoptosis and may produce unwanted consequences in vivo.
Mots clés
3T3 Cells, Animals, Antigens, CD80, genetics, Antigens, CD95, genetics, Apoptosis, genetics, DNA, genetics, DNA Methylation, Fas Ligand Protein, Fibrosarcoma, Genetic Therapy, methods, Genetic Vectors, Humans, Membrane Glycoproteins, genetics, Mice, Plasmids, RNA, Viral, Retroviridae, Signal Transduction, genetics, Transfection, Up-Regulation
Référence
J Gene Med. ;4(1):14-24
