Fiche publication


Date publication

janvier 2017

Journal

Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging

Auteurs

Membres identifiés du Cancéropôle Est :
Pr KARCHER Gilles , Pr MARIE Pierre-Yves , Pr VERGER Antoine


Tous les auteurs :
Poussier S, Maskali F, Vexiau G, Verger A, Boutley H, Karcher G, Raffo E, Marie PY

Résumé

The Statistical Parametric Mapping (SPM) software is frequently used for the quantitative analysis of patients' brain images obtained from 2-deoxy-2-[(18)F]fluoro-D-glucose positron emission tomography ([(18)F]FDG PET). However, its adaptation to small animals is difficult, particularly for the initial step of spatial normalization which requires a specific brain anatomical template. This study was aimed at determining whether SPM analysis can be applied to rat, and more specifically to the lithium-pilocarpine model of epilepsy, by using an adaptive template. This template developed for PET clinical imaging is constructed from a block matching algorithm.

Référence

Mol Imaging Biol. 2017 Jan;: