Fiche publication


Date publication

septembre 2017

Journal

Trends in biochemical sciences

Auteurs

Membres identifiés du Cancéropôle Est :
Dr KLAHOLZ Bruno


Tous les auteurs :
Klaholz BP

Résumé

The central dogma of molecular biology comprises two fundamental mechanistic steps of gene expression (transcription and translation), which, in bacteria, are coupled. A recent study provides structural insights into a supercomplex between the RNA polymerase and the ribosome, thus highlighting the synergy between two key macromolecular machineries in the cell.

Mots clés

RNA polymerase, bacteria, gene expression, ribosome, transcription, translation

Référence

Trends Biochem. Sci.. 2017 09;42(9):686-689