Fiche publication


Date publication

décembre 2016

Journal

Critical care (London, England)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ALBUISSON Eliane


Tous les auteurs :
Wei C, Louis H, Schmitt M, Albuisson E, Orlowski S, Levy B, Kimmoun A

Résumé

Administration of a selective β1-blocker, such as esmolol, in human septic shock has demonstrated cardiovascular protective effects related to heart rate reduction. Certain experimental data also indicate that esmolol exerts systemic anti-inflammatory and beneficial effects on vascular tone. Thus, the present study aimed to determine whether a non-chronotropic dose of esmolol maintains its protective cardiovascular and anti-inflammatory effects in experimental septic shock.

Référence

Crit Care. 2016 Dec;20(1):407