Fiche publication
Date publication
décembre 2016
Journal
Critical care (London, England)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ALBUISSON Eliane
Tous les auteurs :
Wei C, Louis H, Schmitt M, Albuisson E, Orlowski S, Levy B, Kimmoun A
Lien Pubmed
Résumé
Administration of a selective β1-blocker, such as esmolol, in human septic shock has demonstrated cardiovascular protective effects related to heart rate reduction. Certain experimental data also indicate that esmolol exerts systemic anti-inflammatory and beneficial effects on vascular tone. Thus, the present study aimed to determine whether a non-chronotropic dose of esmolol maintains its protective cardiovascular and anti-inflammatory effects in experimental septic shock.
Référence
Crit Care. 2016 Dec;20(1):407