Epidermal growth factor receptor and v-Ki-ras2 Kirsten rat sarcoma viral oncogen homologue-specific amino acid substitutions are associated with different histopathological prognostic factors in resected non-small-cell lung cancer.

Date publication

décembre 2016

Journal

Interactive cardiovascular and thoracic surgery

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BEAU-FALLER Michèle , Pr CHENARD Marie-Pierre , Pr FALCOZ Pierre-Emmanuel , Pr OLLAND Anne

Tous les auteurs :
Seitlinger J, Renaud S, Falcoz PE, Schaeffer M, Olland A, Reeb J, Santelmo N, Legrain M, Voegeli AC, Weingertner N, Chenard MP, Beau-Faller M, Massard G

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/27530493

Résumé

Epidermal growth factor receptor (mEGFR) and v-Ki-ras2 Kirsten rat sarcoma viral oncogen homologue (mKRAS) mutations are the two main oncogenic drivers in resected non-small-cell lung cancer (NSCLC). We aimed to evaluate the correlation between histopathological prognostic factors and these mutations in resected NSCLC.

Référence

Interact Cardiovasc Thorac Surg. 2016 Dec;23(6):902-907