Fiche publication
Date publication
décembre 2016
Journal
Clinical nuclear medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ROHR Serge
,
Pr IMPERIALE Alessio
Tous les auteurs :
Helali M, Heimburger C, Rohr S, Goichot B, Imperiale A
Lien Pubmed
Résumé
The localization of small bowel (SB) neuroendocrine tumors (NETs) remains a diagnostic challenge in clinical practice. In about a third of cases, SB-NETs are multiple at diagnosis. However, the sensitivity of conventional presurgical diagnostic investigations is not exhaustive. F-FDOPA (6-L-F-fluorodihydroxyphenylalanine) PET seems to be a valuable diagnostic technique for the detection of midgut NETs. According to our experience, a delayed PET/CT acquisition centered on abdominopelvic region and performed after oral hydration may improve the detection of primary tumor and the identification of patients with multifocal SB-NETs who could benefit from a more accurate intraoperative palpation of the entire SB.
Mots clés
Adult, Carcinoid Tumor, diagnostic imaging, Dihydroxyphenylalanine, analogs & derivatives, Female, Fluorine Radioisotopes, Humans, Intestinal Neoplasms, diagnostic imaging, Male, Middle Aged, Neuroendocrine Tumors, diagnostic imaging, Positron Emission Tomography Computed Tomography, methods
Référence
Clin Nucl Med. 2016 Dec;41(12):944-945