Cockayne syndrome: a diffusion tensor imaging and volumetric study.

Date publication

novembre 2016

Journal

The British journal of radiology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MEYER Nicolas

Tous les auteurs :
Koob M, Rousseau F, Laugel V, Meyer N, Armspach JP, Girard N, Dietemann JL

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/27643390

Résumé

Cockayne syndrome (CS) is a rare disorder characterized by severe brain atrophy, white matter (WM) hypomyelination and basal ganglia calcifications. This study aimed to quantify atrophy and WM abnormalities using diffusion tensor imaging (DTI) and volumetric analysis, to evaluate possible differences between CS subtypes and to determine whether DTI findings may correspond to a hypomyelinating disorder.

Mots clés

Adolescent, Adult, Anisotropy, Case-Control Studies, Child, Child, Preschool, Cockayne Syndrome, diagnostic imaging, Diffusion Tensor Imaging, methods, Female, Humans, Image Interpretation, Computer-Assisted, Imaging, Three-Dimensional, Infant, Male

Référence

Br J Radiol. 2016 Nov;89(1067):20151033