Fiche publication
Date publication
août 2019
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Lien Pubmed
Résumé
The conservative treatment of squamous cell carcinoma of anal canal by irradiation is recommended as first indication. Despite its rarity, significant improvements were obtained by retrospective or prospective clinical studies these 20 past years, evaluating concomitant chemotherapy and IMRT. Nevertheless, the individualisation of the treatment, over dose distribution, has poor data available. Fractionation remains classic (1.8-2.0Gy/Fr), but the optimal dose level remains under discussion. The strategy concerning the volumes and doses for the prophylactic volumes remains under discussion. This paper will describe the data published, and the recommendations of working Groups, and the main options under evaluation. To conclude, today only the absence of gap is recommended, the benefit of a one-step schedule reducing the treatment time, then increasing local control and survival, but personalised schedules remain under investigation.
Mots clés
Brachytherapy, Curiethérapie, Dose, IMRT, RCMI, Treatment duration, Volumes, étalement
Référence
Cancer Radiother. 2019 Aug 27;:
