Fiche publication


Date publication

novembre 2016

Journal

Osteoarthritis and cartilage

Auteurs

Membres identifiés du Cancéropôle Est :
Pr JOUZEAU Jean-Yves , Pr MAINARD Didier


Tous les auteurs :
Bianchi A, Guibert M, Cailotto F, Gasser A, Presle N, Mainard D, Netter P, Kempf H, Jouzeau JY, Reboul P

Résumé

Fibroblast Growth Factor 23 (FGF23) may represent an attractive candidate that could participate to the osteoarthritic (OA)-induced phenotype switch of chondrocytes. To address this hypothesis, we investigated the expression of FGF23, its receptors (FGFRs) and co-receptor (Klotho) in human cartilage and studied the effects of rhFGF23 on OA chondrocytes.

Référence

Osteoarthr. Cartil.. 2016 Nov;24(11):1961-1969