Fiche publication


Date publication

novembre 2016

Journal

Human immunology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BAHRAM Siamak , Dr CARAPITO Raphaël


Tous les auteurs :
Bahram S, Carapito R, Gourraud PA, Charron D

Résumé

TRANSPLANTEX, a French "investment for the future" initiated consortium of leading transplant units and research laboratories across France and a number of European countries aims to unravel, through mainly high-throughput genomics (and other omics) analyses of donor and recipients, novel (a) non-HLA, histocompatibility antigens, whether inside, or outside the MHC; (b) pre/post transplantation biomarkers. This shall lead to our better understanding of the pathophysiology of (and eventually designing better therapeutics for) the graft-versus-host disease in hematopoietic cell transplants and that of chronic graft rejection after kidney transplant. Industrial developments as well as innovative teaching initiatives are also integral part of this program. The present issue of Human Immunology aims to present a first snapshot of some of the research performed by TRANPLANTEX partners.

Mots clés

Biomarkers, metabolism, Consensus, France, Graft Rejection, diagnosis, Graft vs Host Disease, diagnosis, Histocompatibility Testing, Humans, Immunosuppression, Kidney Transplantation, Registries

Référence

Hum. Immunol.. 2016 Nov;77(11):1005-1007