Realtime Tracking of the Photobleaching Trajectory During Photodynamic Therapy.

Date publication

octobre 2016

Journal

IEEE transactions on bio-medical engineering

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BARBERI-HEYOB Muriel , Pr BASTOGNE Thierry , Dr FROCHOT Céline

Tous les auteurs :
Tylcz JB, Bastogne T, Bourguignon A, Frochot C, Barberi-Heyob M

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/27775901

Résumé

Photodynamic therapy (PDT) is an alternative treatment for cancer that involves the administration of a photosensitizing agent, which is activated by light at a specific wavelength. This illumination causes after a sequence of photoreactions, the production of reactive oxygen species responsible for the death of the tumor cells but also the degradation of the photosensitizing agent, which then loose the fluorescence properties. The phenomenon is commonly known as photobleaching process and can be considered as a therapy efficiency indicator.

Référence

IEEE Trans Biomed Eng. 2016 Oct;: