Fiche publication
Date publication
novembre 2015
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MELY Yves
Tous les auteurs :
Collot M, Kreder R, Tatarets AL, Patsenker LD, Mely Y, Klymchenko AS
Lien Pubmed
Résumé
A rational design of squaraine dyes with lipophilic and zwitterionic groups tunes cell entry, allowing for selective far-red/near-infrared imaging of plasma membrane vs. endoplasmic reticulum. They exhibit up to 110-fold fluorescence enhancement in biomembranes and enable cellular imaging at 1 nM concentration, which make them the brightest membrane probes to date.
Référence
Chem Commun (Camb). 2015 Nov 19;51(96):17136-9
