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Date publication
septembre 2019
Journal
Anaerobe
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BERNARD Alain
Tous les auteurs :
Seibel J, Rebibou JM, Bonnot PH, Bernard A, Zanetta G, Tetu J, Legendre M
Lien Pubmed
Résumé
Fusobacterium nucleatum is a common oral commensal bacterium capable of severe invasive infections. We report a case of a diffuse bilateral pneumopathy with F. nucleatum-positive blood culture successfully treated by common antibiotics in a patient receiving eculizumab for a drug-induced thrombotic microangiopathy (TMA). It is the first described case of a severe F. nucleatum-associated infection in a patient undergoing terminal complement inhibitor therapy. We suggest providing preventive dental care before eculizumab initiation.
Mots clés
Fusobacterium nucleatum, eculizumab, periodontitis, pneumopathy
Référence
Anaerobe. 2019 Sep 9;:102099
