Fiche publication


Date publication

avril 2014

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BAUMERT Thomas


Tous les auteurs :
Fauvelle C, Felmlee DJ, Baumert TF

Résumé

The high variability and the limited knowledge of the structure of the hepatitis C virus (HCV) envelope glycoproteins (GP) are challenging hurdles for vaccine design. Recently, Kong et al. published a new model of HCV E2 GP structure in Science, revealing a globular structure, starkly contrasting from the extended model of class II fusion proteins from other Flaviviridae viruses.

Référence

Cell Res. 2014 Apr;24(4):385-6