Fiche publication
Date publication
septembre 2019
Journal
JMIR research protocols
Auteurs
Membres identifiés du Cancéropôle Est :
Dr AMIOT Clotilde
,
Dr PAZART Lionel
,
Pr ROUX Christophe
Tous les auteurs :
Pretalli JB, Frontczak Franck S, Pazart L, Roux C, Amiot C,
Lien Pubmed
Résumé
Sterility is a major late effect of radiotherapy and chemotherapy treatments. Iatrogenic sterility is often permanent and greatly impacts long-term quality of life. Ovarian tissue cryopreservation (OTC) performed before gonadotoxic treatments with subsequent autograft is a method of fertility preservation available for girls and women. Its application in prepubertal girls is of particular value as it is the only possible approach in this patient group. In addition, it does not require a delay in cancer therapy and no ovarian stimulation is needed.
Mots clés
cohort study, cryopreservation, fertility preservation, live birth rate, ovarian tissue, pregnancy rate
Référence
JMIR Res Protoc. 2019 09 30;8(9):e12944
