Fiche publication


Date publication

avril 2006

Journal

Journal of perinatology : official journal of the California Perinatal Association

Auteurs

Membres identifiés du Cancéropôle Est :
Dr OJEDA-URIBE Mario , Dr DRENOU Bernard


Tous les auteurs :
Ojeda-Uribe M, Gilliot C, Jung G, Drenou B, Brunot A

Résumé

Rituximab, a chimeric mouse/human monoclonal antibody that binds to the CD20 antigen, is part of current treatment of many B-cell malignancies and several autoimmune diseases. Very few cases of rituximab administration during pregnancy have been described. We report here the case of rituximab administration during the first trimester of pregnancy in a woman with autoimmune hemolytic anemia. No significant effects were observed in B-cell counts or the immune status of the newborn.

Mots clés

Adrenal Cortex Hormones, administration & dosage, Adult, Anemia, Hemolytic, Autoimmune, drug therapy, Antibodies, Monoclonal, administration & dosage, Antibodies, Monoclonal, Murine-Derived, Antirheumatic Agents, administration & dosage, Drug Therapy, Combination, Erythrocyte Transfusion, Female, Humans, Infant, Newborn, Pregnancy, Pregnancy Complications, Hematologic, drug therapy, Pregnancy Outcome, Pregnancy Trimester, First, Recurrence, Rituximab, Treatment Refusal

Référence

J Perinatol. 2006 Apr;26(4):252-5