A rare case of extremely high counts of circulating tumor cells detected in a patient with an oral squamous cell carcinoma.

Date publication

juillet 2016

Journal

BMC cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DE CARVALHO BITTENCOURT Marcelo , Pr DOLIVET Gilles , Pr FAURE Gilbert , Dr MASTRONICOLA Romina

Tous les auteurs :
Wu X, Mastronicola R, Tu Q, Faure GC, De Carvalho Bittencourt M, Dolivet G

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/27465596

Résumé

Despite aggressive regimens, the clinical outcome of head and neck squamous cell carcinoma remains poor. The detection of circulating tumor cells could potentially improve the management of patients with disseminated cancer, including diagnosis, treatment strategies, and surveillance. Currently, CellSearch(®) is the most widely used and the only Food and Drug Administration-cleared system for circulating tumor cells detection in patients with metastatic breast, colorectal, or prostate cancer. In most cases of head and neck squamous cell carcinoma, only low counts of circulating tumor cells have been reported.

Référence

BMC Cancer. 2016 Jul;16:552