Stretch-induced Activation of Transforming Growth Factor-β1 in Pulmonary Fibrosis.

Date publication

juillet 2016

Journal

American journal of respiratory and critical care medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BELLAYE Pierre-Simon

Tous les auteurs :
Froese AR, Shimbori C, Bellaye PS, Inman M, Obex S, Fatima S, Jenkins G, Gauldie J, Ask K, Kolb M

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/26771871

Résumé

Recent findings suggesting transforming growth factor (TGF)-β1 activation by mechanical stimuli in vitro raised the question of whether this phenomenon was relevant in vivo in the context of pulmonary fibrosis.

Mots clés

mechanical stress, mechanotransduction, pulmonary fibrosis, transforming growth factor-β1, ventilation

Référence

Am. J. Respir. Crit. Care Med.. 2016 07 1;194(1):84-96