First case report of an adrenocortical carcinoma caused by a BRCA2 mutation.

Date publication

septembre 2016

Journal

Medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Dr MAUGARD Christine

Tous les auteurs :
El Ghorayeb N, Grunenwald S, Nolet S, Primeau V, Côté S, Maugard CM, Lacroix A, Gaboury L, Bourdeau I

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/27603373

Résumé

Adrenocortical carcinoma (ACC) may rarely be a component of inherited cancer syndromes such as Li-Fraumeni syndrome and Beckwith-Wiedemann syndrome. ACC caused by a BRCA2 mutation has never been reported.

Mots clés

Adrenal Cortex Neoplasms, genetics, Adrenocortical Carcinoma, genetics, Adult, Breast Neoplasms, genetics, Female, Genes, BRCA2, Germ-Line Mutation, Heterozygote, Humans, Male, Middle Aged, Pedigree

Référence

Medicine (Baltimore). 2016 Sep;95(36):e4756