Fiche publication


Date publication

avril 2014

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GHIRINGHELLI François , Dr BRUCHARD Mélanie


Tous les auteurs :
Bruchard M, Ghiringhelli F

Résumé

Immunosuppression is a mechanism developed by cancer cells to help them escape the immune system. Immunosuppression involves expansion of various cell types and production of a variety of cytokines. In this review, we explore the duality of three cancer induced cell populations, regulatory T lymphocytes, Th17 lymphocytes and MDSC, and also the pleiotropic effects of several cytokines induced during cancer development.

Référence

Med Sci (Paris). 2014 Apr;30(4):429-35