Fiche publication
Date publication
décembre 2019
Journal
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent
Tous les auteurs :
Allocca M, Danese S, Laurent V, Peyrin-Biroulet L
Lien Pubmed
Résumé
A "treat-to-target" strategy with close monitoring of intestinal inflammation is recommended in inflammatory bowel disease (IBD). Ileocolonoscopy (CS) remains the gold-standard for assessing disease activity in IBD but is a relatively invasive procedure and is impossible to repeat in the context of tight monitoring strategies. In addition to biomarkers, cross-sectional imaging is increasingly used in these patients. Computed tomography is limited by the use of radiation, while the use of Magnetic Resonance Enterography (MRE) is limited by its cost and access. There is growing interest in bowel ultrasound (US) that represents a cost-effective, non-invasive and well-tolerated modality in clinical practice, but it is operator dependent. Compared to CS and MRE, bowel US has shown to have the same level of accuracy in assessing and monitoring disease activity for both CD and UC and can thus be considered as a point-of -care test. Diffusion-weighted imaging (DWI) is a MR imaging technique that is increasingly used in both IBD and non-IBD conditions and that has shown to be a valuable and accurate tool for assessing and monitoring IBD activity. Comparing to conventional MRE, DWI is quicker, less time-consuming, may not require intravenous contrast agent, fasting, bowel cleansing, oral or rectal preparation. The aim of this review is to discuss the role of these cross-sectional imaging techniques for the management of patients with IBD. In the near future, the value of DWI and US in assessing IBD will require further investigation in the era of transmural healing in CD and complete mucosal healing, including histologic remission, in UC.
Mots clés
Crohn’s disease, Diffusion-weighted imaging, Ulcerative colitis, bowel ultrasound, imaging, inflammatory bowel disease
Référence
Clin. Gastroenterol. Hepatol.. 2019 Dec 5;:
