Efficacy and Safety of Adjuvant Proton Therapy Combined With Surgery for Chondrosarcoma of the Skull Base: A Retrospective, Population-Based Study.

Date publication

mai 2016

Journal

International journal of radiation oncology, biology, physics

Auteurs

Membres identifiés du Cancéropôle Est :
Pr NOEL Georges

Tous les auteurs :
Feuvret L, Bracci S, Calugaru V, Bolle S, Mammar H, De Marzi L, Bresson D, Habrand JL, Mazeron JJ, Dendale R, Noël G

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/26883563

Résumé

Chondrosarcoma is a rare malignant tumor of the cartilage affecting young adults. Surgery, followed by charged-particle irradiation, is considered the reference standard for the treatment of patients with grade I to II skull base chondrosarcoma. The present study was conducted to assess the effect of the quality of surgery and radiation therapy parameters on local control (LC) and overall survival (OS).

Mots clés

Adolescent, Adult, Aged, Aged, 80 and over, Child, Chondrosarcoma, mortality, Follow-Up Studies, Humans, Middle Aged, Neoplasm Recurrence, Local, Organ Sparing Treatments, Organs at Risk, Photons, therapeutic use, Proton Therapy, adverse effects, Radiotherapy, Adjuvant, adverse effects, Relative Biological Effectiveness, Retrospective Studies, Skull Base Neoplasms, mortality, Survival Rate, Time Factors, Tumor Burden

Référence

Int. J. Radiat. Oncol. Biol. Phys.. 2016 May;95(1):312-21