Fatal acute respiratory distress by Toxoplasma gondii in a toxoplasma seronegative liver transplant recipient.

Date publication

avril 2016

Journal

The new microbiologica

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DI MARTINO Vincent , Pr HEYD Bruno

Tous les auteurs :
Miltgen G, Paillot J, Vanlemmens C, Di Martino V, Heyd B, Millon L, Bellanger AP

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/27196559

Résumé

The risk of Toxoplasma gondii infection in solid organ transplant recipients is well known but mainly after heart transplantation. We discuss a case of acute respiratory distress caused by Toxoplasma gondii on Day 32 after liver transplantation. The reported case, which is extremely rare, emphasizes how direct examination and Quantitative Polymerase Chain Reaction (QPCR) in broncholaveolar lavage help to diagnose the infection. Given Trimethoprim/Sulfamethoxazole toxicity, systematic prescription of Toxoplasma gondii chemoprophylaxis is not commonly approved in liver transplantation.

Mots clés

Fatal Outcome, Female, Humans, Immunocompromised Host, Liver Transplantation, adverse effects, Lung Diseases, Parasitic, etiology, Middle Aged, Tissue Donors, Toxoplasmosis, pathology

Référence

New Microbiol.. 2016 Apr;39(2):160-2