Fiche publication


Date publication

avril 2016

Journal

The British journal of dermatology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr AUBIN François


Tous les auteurs :
Samimi M, Molet L, Fleury M, Laude H, Carlotti A, Gardair C, Baudin M, Gouguet L, Maubec E, Avenel-Audran M, Esteve E, Wierzbicka-Hainaut E, Beneton N, Aubin F, Rozenberg F, Dupin N, Avril MF, Lorette G, Guyetant S, Coursaget P, Touzé A

Résumé

Merkel cell polyomavirus (MCPyV) is the main aetiological agent of Merkel cell carcinoma (MCC). Serum antibodies against the major MCPyV capsid protein (VP1) are detected in the general population, whereas antibodies against MCPyV oncoproteins (T antigens) have been reported specifically in patients with MCC.

Mots clés

Adult, Aged, Aged, 80 and over, Antigens, Viral, Tumor, blood, Biomarkers, Tumor, blood, Capsid Proteins, blood, Carcinoma, Merkel Cell, immunology, Enzyme-Linked Immunosorbent Assay, Female, Humans, Kaplan-Meier Estimate, Male, Merkel cell polyomavirus, immunology, Middle Aged, Neoplasm Recurrence, Local, immunology, Polyomavirus Infections, immunology, Prognosis, Risk Assessment, methods, Skin Neoplasms, immunology, Tumor Virus Infections, immunology

Référence

Br. J. Dermatol.. 2016 Apr;174(4):813-22