Impact of conditioning intensity in T-replete haplo-identical stem cell transplantation for acute leukemia: a report from the acute leukemia working party of the EBMT.

Date publication

mars 2016

Journal

Journal of hematology & oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr RUBIO Marie Thérèse

Tous les auteurs :
Rubio MT, Savani BN, Labopin M, Piemontese S, Polge E, Ciceri F, Bacigalupo A, Arcese W, Koc Y, Beelen D, Gülbas Z, Wu D, Santarone S, Tischer J, Afanasyev B, Schmid C, Giebel S, Mohty M, Nagler A

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/26980295

Résumé

Increasing numbers of patients are receiving haplo-identical stem cell transplantation (haplo-SCT) for treatment of acute leukemia with reduced intensity (RIC) or myeloablative (MAC) conditioning regimens. The impact of conditioning intensity in haplo-SCT is unknown.

Mots clés

Acute Disease, Adult, Antineoplastic Combined Chemotherapy Protocols, therapeutic use, Cyclophosphamide, administration & dosage, Cytarabine, administration & dosage, Disease-Free Survival, Female, Graft vs Host Disease, prevention & control, Hematopoietic Stem Cell Transplantation, methods, Humans, Leukemia, Myeloid, therapy, Male, Melphalan, administration & dosage, Middle Aged, Multivariate Analysis, Mycophenolic Acid, administration & dosage, Neoplasm Recurrence, Local, Precursor Cell Lymphoblastic Leukemia-Lymphoma, therapy, Retrospective Studies, Transplantation Conditioning, methods, Treatment Outcome

Référence

J Hematol Oncol. 2016 Mar 15;9:25