Fiche publication


Date publication

janvier 2016

Journal

European journal of cancer (Oxford, England : 1990)

Auteurs

Membres identifiés du Cancéropôle Est :
Dr RIOS Maria


Tous les auteurs :
Patrikidou A, Domont J, Chabaud S, Ray-Coquard I, Coindre JM, Bui-Nguyen B, Adenis A, Rios M, Bertucci F, Duffaud F, Chevreau C, Cupissol D, Pérol D, Emile JF, Blay JY, Le Cesne A,

Résumé

The added value of tumoural genomic profiles to conventional clinico-biological factors to predict progression-free survival (PFS) and overall survival (OS) was prospectively investigated in patients with advanced gastrointestinal stromal tumours (GIST) treated in the BFR14 study.

Mots clés

Antineoplastic Agents, administration & dosage, Biomarkers, Tumor, genetics, DNA Mutational Analysis, Disease-Free Survival, Exons, Female, France, Gastrointestinal Neoplasms, drug therapy, Gastrointestinal Stromal Tumors, drug therapy, Humans, Imatinib Mesylate, administration & dosage, Kaplan-Meier Estimate, Male, Mutation, Predictive Value of Tests, Proportional Hazards Models, Protein Kinase Inhibitors, administration & dosage, Proto-Oncogene Proteins c-kit, genetics, Risk Factors, Time Factors, Treatment Outcome

Référence

Eur. J. Cancer. 2016 Jan;52:173-80