Genotypic study of Citrobacter koseri, an emergent platelet contaminant since 2012 in France.

Date publication

février 2020

Journal

Transfusion

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HOCQUET Didier

Tous les auteurs :
Emery A, Marpaux N, Naegelen C, Valot B, Morel P, Hocquet D

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/31804713

Résumé

Transfusion-transmitted bacterial infection is a rare occurrence but the most feared complication in transfusion practices. Between 2012 and 2017, five cases of platelet concentrates (PCs) contaminated with the bacterial pathogen Citrobacter koseri (PC-Ck) have been reported in France, with two leading to the death of the recipients. We tested the possibilities of the emergence of a PC-specific clone of C. koseri (Ck) and of specific bacterial genes associated with PC contamination.

Référence

Transfusion. 2020 Feb;60(2):245-249